The other majorly researched use
of psychedelics is in easing anxiety and depression stemming from terminal
illness and fear of death, especially in end-stage cancer patients. There are many studies currently under way
using LSD or psilocybin pills to treat anxiety and depression in cancer
patients. A study was just
completed by psychiatrist Charles Grob at Harbor-UCLA Medical Center that found
that psilocybin can be administered safely while reducing anxiety and
depression in end-stage cancer patients.
In the study, Grob brought subjects into a hospital room that had been
draped in sheets and with extra furnishings to create a more comfortable
environment, and the subjects brought pictures and other objects with
sentimental value, and the subject would discuss these pictures and objects
with the doctor and assistants while they administered the drug. This created a positive mindset in the
patients, who would then listen to music with a blindfold on while they were
experiencing the psilocybin trip. The
subjects showed significant reduction in depression and anxiety for 6 months
after the drug was administered. The
psilocybin, in 20-30 milligrams doses, gave the subjects mystical insight into
their life position, and caused “sustained positive changes in attitude, mood
and behavior” (Slater). The subjects
reported that they were able to enjoy the time they had left more fully, and
felt grateful for and took advantage of the present, and were more comfortable
with their death. While researchers do
not know how psilocybin and other psychedelic drugs work, it is understood that
ingestion of these substances is "associated with a deactivation of
regions of the brain that integrate our senses and our perception of self"
(Slater). Timothy Leary, one of the
biggest voices for psychedelic research in the 1960's, called this phenomenon
"ego-loss", where the drug user loses his identity and sense of who
he is. Leary said that ego-loss was an
important tool for lasting change because sometimes to change one's identity it
is necessary to lose identity and perceive it from another point of view. This may be the most important
characteristic of psychedelics for the use of therapy and what causes patients given
these drugs to change their outlook on their disease.
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